Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain

Massachusetts General Hospital
RFA-EB-17-001
2017
1R01EB025145-01
Franceschini, Maria Angela
Advancements in non-invasive imaging technology – such as functional near-infrared spectroscopy (fNIRS) – allow for more accurate measurements of human brain function. Maria Franceschini and her team are developing a wearable (and potentially wireless) device that advances fNIRS by employing functional diffuse correlation spectroscopy (fDCS). Current fNIRS methods quantify blood flow by measuring light attenuation, but Franceschini’s DCS method captures both hemoglobin concentration and blood flow, leading to better temporal and spatial estimates of neuronal activity, as well as improve spatial resolution by distinguishing between brain and superficial scalp and skull. Development of this fDCS prototype could lead to more accurate and cost-effective methods of imaging human brain function.
Massachusetts General Hospital
United States
42° 21' 48.2004" N, 71° 4' 7.14" W
US
9420764
Funded Status: 
Active