Spinal root stimulation for restoration of function in lower-limb amputees

University Of Pittsburgh At Pittsburgh
RFA-NS-17-006
2017
1UH3NS100541-01A1
Fisher, Lee E (contact) Weber, Douglas J
Despite recent advancements in prosthetics, prosthetic devices still lack a means of providing direct sensory feedback, which would improve balance control, reduce falling risk, and could significantly diminish severe phantom limb pain. In individuals with trans-tibial amputation, Fisher’s team will use spinal cord stimulator leads to electrically stimulate the dorsal root ganglia and dorsal rootlets. They intend to generate sensations of pressure and movement in the amputated limb, and reduce phantom limb pain, which correlates with greater prosthesis use. The group will use electromyography to analyze the relationship between stimulation and evoked reflexive responses, and thus optimize stimulation programming. To improve gait function, the group will study how signals from pressure/angle sensors within the prosthetics can be used to modulate sensory feedback via stimulation. These experiments could assist development of a neuroprosthesis that would improve quality of life for individuals with trans-tibial amputation.
University Of Pittsburgh At Pittsburgh
United States
40° 26' 44.0952" N, 79° 57' 14.1012" W
US
9403325
Funded Status: 
Active