APL researchers are standardizing an amazing collection of high-resolution brain mapping data, an effort that would enable unprecedented analysis and make the Laboratory a focal point for neuroscience research.
This FOA will support integrated, interdisciplinary research teams from prior BRAIN technology and/or integrated approaches teams, and/or new projects from the research community that focus on examining circuit functions related to behavior, using advanced and innovative technologies. The goal will be to support programs with a team science approach that can realize meaningful outcomes within 5-plus years. Awards will be made for 5 years, with a possibility of one competing renewal.
Invasive surgical procedures offer the opportunity for unique intracranial interventions such as the ability to record and stimulate intracranially within precisely localized brain structures in humans. Human studies using invasive technology are often constrained by a limited number of patients and resources available to implement complex experimental protocols and need to be aggregated in a manner that addresses research questions with appropriate statistical power.
3 new projects launch on the Allen Institute's OpenScope, a shared neuroscience observatory, supported by the NIH BRAIN Initiative
Parkinson's disease is marked by the death of dopamine-producing neurons in the brain — specifically in the substantia nigra, a structure deep within a region of the brain called the midbrain.
Researchers have uncovered how signals from a group of neurons in the brain's frontal lobe simultaneously give humans the flexibility to learn new tasks -- and the focus to develop highly specific skills.
UNC School of Medicine researchers led by Ian Shih, Ph.D., used fMRI and a genetic mouse model to study the effects of a neurotransmitter on brain network functional connectivity, a dynamic process crucial for human health and behavior
Implants are becoming more sophisticated — and are attracting commercial interest.
In the diagnosis of disease, doctors often need to take tissue samples and process them for examination under a microscope. Millions of such biopsies are performed in the U.S. every year. But these pose many challenges. Biopsies may damage healthy tissue. Conventional histology techniques used to examine the samples can require extensive processing and take days.
The Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace, NOT-MH-21-125, encourages the translation of BRAIN Initiative-supported technologies from academic and other non-small business research sectors to the marketplace.