In a study of a small region of the thalamus, MIT neuroscientists have now identified three distinct circuits that influence the development of both motor and nonmotor symptoms of Parkinson’s.
APL researchers are standardizing an amazing collection of high-resolution brain mapping data, an effort that would enable unprecedented analysis and make the Laboratory a focal point for neuroscience research.
Parkinson's disease is marked by the death of dopamine-producing neurons in the brain — specifically in the substantia nigra, a structure deep within a region of the brain called the midbrain.
3 new projects launch on the Allen Institute's OpenScope, a shared neuroscience observatory, supported by the NIH BRAIN Initiative
Researchers supported by the National Institutes of Health Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative have developed a way to genetically insert a type of light receptor into neu
In the diagnosis of disease, doctors often need to take tissue samples and process them for examination under a microscope. Millions of such biopsies are performed in the U.S. every year. But these pose many challenges. Biopsies may damage healthy tissue.
Addgene, the nonprofit biorepository, now produces and distributes ready-to-use recombinant antibodies.
Platform will provide open-source cell catalogue to better understand brain diseases.
In a new study on 3D organoid models of the developing cerebral cortex generated from human induced pluripotent stem cells (iPSCs), researchers at the Broad Institute of the Massachusetts Institute of Technology (MIT) and Harvard University have found three autism risk genes converge on shared pa
Understanding of novel functional roles can advance research in Alzheimer’s disease, other learning and memory disorders.
New guide will lead to more rigorous analysis, reproducibility and richer conclusions.
Scientists around the world are working together to catalogue and map cells in the brain. What have these huge projects revealed about how it works?
By Joshua Gordon, M.D., Ph.D., and Walter Koroshetz, M.D., director of the National Institute of Neurological Disorders and Stroke
Massive cell census could better pinpoint targets for treating brain diseases
The Albert Lasker Basic Medical Research Award, largely regarded as America’s top biomedical research prize, was recently awarded to three investigators for their pioneering work on optogenetics, including BRAIN MCWG member Karl Deisseroth.
The 2021 cohort of Howard Hughes Medical Institute (HHMI) Investigators includes six BRAIN-funded scientists.
The NIH-led Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative continues to teach us about the world’s most sophisticated computer: the human brain.