Our sense of smell has a powerful effect on our behavior and emotions. Aromas can evoke vivid memories of the past or warn us of a smoldering fire. Yet to neuroscientists, smell remains the most mysterious of our five senses.
A massive dataset of 1.2M brain cells shines a light on disease’s cellular roots.
In a study of a small region of the thalamus, MIT neuroscientists have now identified three distinct circuits that influence the development of both motor and nonmotor symptoms of Parkinson’s.
Parkinson's disease is marked by the death of dopamine-producing neurons in the brain — specifically in the substantia nigra, a structure deep within a region of the brain called the midbrain.
Platform will provide open-source cell catalogue to better understand brain diseases.
Scientists around the world are working together to catalogue and map cells in the brain. What have these huge projects revealed about how it works?
Atlas and cell census represent the initial products of the BRAIN Initiative Cell Census Network
By Joshua Gordon, M.D., Ph.D., and Walter Koroshetz, M.D., director of the National Institute of Neurological Disorders and Stroke
Massive cell census could better pinpoint targets for treating brain diseases
The 2021 cohort of Howard Hughes Medical Institute (HHMI) Investigators includes six BRAIN-funded scientists.
John Ngai is the Director of the NIH’s Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative.
The National Institutes of Health will fund more than 175 grants, totaling nearly $500 million, through the NIH’s Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative, part of a large effort among federal and non-federal partners to use knowledge about how th
When neuroscientist Sébastien Tremblay set out to manipulate monkeys’ brains with light, colleagues had sobering advice: “It’s more difficult than it sounds.” Tremblay, who works in neuroscientist Michael Platt’s lab at the University of Pennsylvania, uses light to activate or silence precise gro
Cold Spring Harbor Laboratory scientists dramatically improved the efficiency of automated methods for tracing neuronal connections. They taught a computer to recognize different parts of neurons, then used the math of topology to see how those neurons are likely to connect.
Large scientific projects in genomics and astronomy are influential not because they answer any single question but because they enable investigation of continuously arising new questions from the same data-rich sources.
Cold Spring Harbor Laboratory (CSHL) scientists have discovered neurons in the mouse brain that help an animal learn to avoid negative experiences. The cells reside in a part of the brain involved in regulating the motivations that influence behavior.