Dr. Anna Gillespie is a postdoctoral fellow in the lab of Dr. Loren Frank at the University of California, San Francisco. She received her BS in Biology from Stanford University in 2010 and her PhD in Biomedical Sciences from the University of California, San Francisco in 2015. During her graduate work in the lab of Dr. Yadong Huang, Anna identified abnormalities in sharp-wave ripples (SWRs; patterns of hippocampal network activity involved in learning and memory processes) in a mouse model of Alzheimer's disease. As a Simons Collaboration on the Global Brain fellow, her postdoctoral work in the Frank lab has furthered our understanding of how the memory replay associated with SWRs relates to ongoing behavior, and includes the development of a real-time feedback paradigm to promote hippocampal replay. As a BRAIN Initiative investigator, Anna will study how SWRs, hippocampal replay, and other hippocampal spatial representations change with age and will develop real-time manipulation strategies to counter such changes.