Dr. Jie Zheng obtained her bachelor’s degree in Electrical Engineering at Nanjing University in China. She then moved to the United States and received her PhD. in Biomedical Engineering at the University of California, Irvine, co-advised by Dr. Jack Lin and Dr. Robert Knight. Her PhD. work uncovered unidirectional influence from the amygdala to the hippocampus underlying the salient information processing using intracranial electroencephalogram (EEG). She also showed how balanced and bidirectional amygdala-hippocampal interactions can reduce the interference of similar emotional memories. During her postdoc at Boston Children’s Hospital, she received training in human single neuron recording co-advised by Dr. Gabriel Kreiman and Dr. Ueli Rutishauser. She reported neurons in the human brain that respond to cognitive boundaries and help construct discrete mnemonic episodes from the continuous experience. Her proposed project will continue studying how memories of the dynamic experience are formed, maintained, and retrieved to influence behaviors. She will receive training under a team of distinguished mentors (Dr. Gabriel Kreiman, Dr. Ueli Rutishauser, Dr. Adam Mamelak, Dr. Ziv Williams) and incorporate behavior measurements, human single neuron recording, computational modeling, and electrical stimulation to address this research question. The expected outcomes of the study will strengthen our understanding of the human memory system and potentially advance the development of therapeutic interventions for memory-related disorders.