Researchers Fully Map Neural Connections of the Fruit Fly Brain
NIH-supported milestone will advance understanding of brain processes in larger animals.
NIH-supported milestone will advance understanding of brain processes in larger animals.
The BRAIN Initiative® Conference, previously known as the BRAIN Initiative Meeting, convenes BRAIN Initiative awardees, staff, and leadership from the contributing federal agencies (NIH, NSF, DARPA, IARPA, and FDA), plus representatives and investigators from participating non-federal organizations, and members of the media, public, and Congress.
A small feasibility study funded by the National Institutes of Health (NIH) found that an implanted device regulated by the body’s brain activity could provide continual and improved treatment for the symptoms of Parkinson’s disease (PD)
In recent years, the NIH has awarded over $850M annually to the numerous research institutions and hospitals within the Texas Medical Center (TMC; Houston, TX), producing ever-increasing numbers of biomedical discov- eries.
Magnetic Resonance Imaging (MRI) is the gold-standard method for the detection and diagnosis of brain disease and surgical planning. Neurosurgery is closely guided by preoperative neuroimaging with MRI which can accurately localize and delineate lesions, map functionally critical brain regions, or probe tissue metabolism to guide clinical management. While the preoperative images are regularly consulted in the OR, the surgeon’s ability to navigate with these maps is degraded by tissue deformation and brain shifts that occur during surgery.
The goal of this project is to create two prototypes of a novel live spike sorting system which can be used by investigators to spike sort streams of neural data recorded by multi-channel, high channel and ultra-high channel probes. In most in-vivo extracellular recording conditions, an electrode can pick up neural spikes from several nearby neurons resulting in so-called “multi-unit” activity in the recording trace.