The BRAIN Initiative® Conference, previously known as the BRAIN Initiative Meeting, convenes BRAIN Initiative awardees, staff, and leadership from the contributing federal agencies (NIH, NSF, DARPA, IARPA, and FDA), plus representatives and investigators from participating non-federal organizations, and members of the media, public, and Congress.
John Ngai, director of the U.S. National Institutes of Health’s BRAIN Initiative, and U.S. Rep. Bonnie Watson Coleman visited in May with Princeton Neuroscience Institute (PNI) researchers to discuss recent advances toward understanding the fundamental workings of the brain.
CRCNS US-German Research Proposal: Quantitative and computational dissection of glutamatergic crosstalk at tripartite synapses (1) Christine R Rose, Heinrich Heine University, Düsseldorf, Germany (2) Christian Henneberger, University of Bonn, Germany (3) Ghanim Ullah, University of South Florida, Tampa, FL, USA Project Description 1 Introduction and Background Transmission at chemical synapses is the central mechanism by which information is transferred between neurons.
PROJECT SUMMARY The maintenance and function of the nervous system depends on cell-cell interactions among neuronal and non-neuronal cell populations, which occur through physically binding cell membrane surface or secreted proteins, triggering signaling cascades that activate cell-type gene regulatory programs. The cell-cell interactome responds and regulates the microenvironment which is altered in physiological processes such as brain development and aging, or during the onset and progression of different neuropsychiatric disorders.
