The NIH BRAIN Initiative U24 funding opportunity provides up to 5 years of support to projects aiming to broadly disseminate developed and validated tools and resources, that are highly relevant to specific goals of the BRAIN Initiative. Below are useful resources for those interested in applying to the U24 program, as well as those interested in using the tools and technologies that are being disseminated by funded U24 projects.
Key Resources
- Milestone Template(pdf, 150 KB)
- Frequently Asked Questions for U24 applicants
- U24 Informational Webinar slides(pdf, 202 KB) and recording (see below)
Current U24 Projects
File
| Name | Description | Category | Contact/PI |
|---|---|---|---|
| Open Ephys GUI | Software for processing, recording, and visualizing multichannel electrophysiology data. | Neurophysiology - Nonhuman | Josh Siegle |
| Neuroscience Monoclonal Antibody Sequencing Initiative (NeuroMabSeq) | Renewable recombinant antibodies and affinity reagents for neuroscience research. | Neural Histology | Jim Trimmer |
| MoSeq | An interactive pipeline and toolkit for unsupervised discovery of repeated motifs in 3D video of freely behaving mice. | Behavioral Neuroscience | Sandeep Robert Datta |
| Two-photon spectrometer | Resource for multiphoton characterization of genetically-encoded fluorescent probes. | Circuit Analysis Reagents | Mikhail Drobizhev |
| Polymer Implantable Electrode (PIE) Foundry | A service to expand access to polymer-based microelectrode arrays, by providing user training, quality control testing, and custom-made devices and tools. | Neurophysiology - Nonhuman | Ellis Meng |
| OpenScope | A community-driven brain observatory for large-scale systems neuroscience. | Neurophysiology - Nonhuman | Jerome Lecoq |
| Neurodata Without Borders (NWB) | Neurodata Without Borders: Neurophysiology (NWB:N) is a data standard for neurophysiology, providing neuroscientists with a common standard to share, archive, use, and build analysis tools for neurophysiology data. | Neuroinformatics | Oliver Ruebel |
| DataJoint Elements | Standardized workflows for neurophysiology experiments, managing data and automated analyses. | Neuroinformatics | Dimitri Yatsenko |
| OpenMind Software Tools | Documented software code developed and shared by OpenMind Consortium members to faciliate research using bidirectional deep-brain stimulation devices. | Neurophysiology - Human | Heather Dawes |
| OpenMind Regulatory Resources | An Open Science Framework webiste hosting shared regulatory and technical information relating to the use of bidirectional deep-brain stimulation devices in clinical research. | Neurophysiology - Human | Heather Dawes |
| BCI2000 | A general-purpose software platform for research and development of adaptive neurotechnologies. | Neurophysiology - Human | Peter Brunner |
| Harvard Connectomics Facility | Tools and training for serial section scanning electron microscopy | Connectomics | Jeff Lichtman |
| National Center for Microscopy and Imaging Research (NCMIR) | Provides access and support in the integrative use of advanced, high throughput multiscale imaging technologies, tools and analysis strategies for brain research | Connectomics | Mark Ellisman |
| Addgene Antibody Open Resource | Recombinant antibodies for neuroscience research in plasmid/protein format and data about their usage | Neural Histology | Melina Fan |
| NeuroJSON | JSON-based open standards and tools to make neuroimaging data human-readable, universally parsable, reusable and discoverable | Neuroinformatics | Qianqian Fang |
| Brain Modeling Tools: BMTK | Comprehensive user support and a dissemination platform for the software tools that facilitate many aspects of modeling in neuroscience, including the Brain Modeling ToolKit (BMTK) software suite for model building/simulation. | Neuroinformatics | Anton Arkhipov |
| Brain Modeling Tools: VND | Comprehensive user support and a dissemination platform for the software tools that facilitate many aspects of modeling in neuroscience, including the Visual Neuronal Dynamics (VND), which offers powerful 3D visualization capabilities for neuronal network models. | Neuroinformatics | Anton Arkhipov |
| Brain Modeling Tools: SONATA | Comprehensive user support and a dissemination platform for the software tools that facilitate many aspects of modeling in neuroscience, including the SONATA file format for efficient storage of model and simulation data. | Neuroinformatics | Anton Arkhipov |
| Human Neocortical Neurosolver (HNN) | The Human Neocortical Neurosolver (HNN) is an open source software platform for cellular and circuit level investigation of human magneto- and electro-encephalography (MEG/EEG) signals. | Neuroinformatics | Stephanie Jones |
| MAPseq/BARseq Core Facility | Providing services and consultations on mapping long-range projections of neurons at single-cell resolution by cellular barcoding and sequencing | Circuit Analysis Reagents | Huiqing/Ching Zhan |
| Center for Advanced Motor Bio-Engineering and Research (CAMBER) | Creation and dissemination of high density electrode arrays ("Myomatrix arrays") for recording muscle activity | Neurophysiology- Nonhuman | CAMBER team |
| Stanford Program for Integrated Neuroscience Technologies (SPrINT) | Platform for the integration of innovative technologies in animal behavior, disease models, neuroimaging, gene and viral vector technologies and human brain organogenesis to external investigators | Behavioral Neuroscience, Circuit Analysis Reagents | Emily Chu |
| UNC Neuroscience NeuroTools | Custom adeno-associated virus (AAV), rabies (RBV), lenti (LV), and herpes simplex virus (HSV) vectors for the neuroscience community using specialized purification strategies | Circuit Analysis Reagents | Kim Ritola |
| Cell Type Knowledge Explorer | A web tool for exploration of cell types in primary motor cortex that span data modalities, species, and levels of resolution | Neuroinformatics | Jeremy Miller |
| Allen Brain Cell (ABC) Atlas | A platform for visualizing and analyzing multimodal single cell and spatial transcriptomics data across the whole mammalian brain in multiple datasets simultaneously | Neuroinformatics | Jeremy Miller |
| MapMyCells | A web tool that allows scientists worldwide to assign cell types to their own transcriptomics and spatial data by comparing their data to mouse and human brain atlases derived by the Allen Institute for Brain Science and BICAN | Neuroinformatics | Jeremy Miller |
| NeuroImaging Chart (NiChart) | NiChart is a framework that integrates modular software tools designed for robust image processing, data analysis, and the development and application of machine learning-based neuroimaging models | Neuroimaging | Guray Erus |