Funded Awards
The National Institutes of Health (NIH) BRAIN Initiative funds a wide-variety of research: toolmakers, trainees, individual labs testing new hypotheses, and large, team-based efforts aiming to catalyze neuroscience inquiry forward. Explore NIH BRAIN Initiative funded awards listed below. Click on the project title to learn more about it within NIH RePORTER.
To see more NIH-funded awards and associated publications, please visit the NIH RePORTER.
Title
Investigator(s)
Institution
Fiscal Year
Funding Opportunity #
Project #
TitleNetwork based neuro-modulation for mesial temporal lobe epilepsy
Investigator
Behnaam Aazhang, Sandipan Pati Bankim Behari Pati, Nitin Tandon, Gregory A Worrell
Institute
university of texas hlth sci ctr houston
Fiscal Year
Funding Opportunities Number
Project Number
TitleNeural mechanisms of behavioral coordination in Hydra
Investigator
Alison Hanson
Institute
columbia university health sciences
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT SUMMARY
How do animals coordinate their many parts to generate coherent, adaptive behavior?
TitleNEURODEVELOPMENTAL FUNCTION OF HCFC1
Investigator
Victoria L Castro
Institute
university of texas el paso
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary
Mutation of HCFC1 causes a multiple congenital anomaly syndrome characterized by inborn errors of cobalamin
metabolism, intractable epilepsy, intellectual disability, and motor dysfunction.
TitleNeurodevelopmental role of a tRNA methyltransferase underlying intellectual disability
Investigator
Kimberly Rose R. Madhwani
Institute
brown university
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT SUMMARY
Gene regulation at multiple levels is critical for nervous system development and function.
TitleNeurostimulation of the Nucleus Basalis of Meynert for the cognitive-motor syndrome in Parkinson's disease
Investigator
Helen Bronte-Stewart
Institute
stanford university
Fiscal Year
Funding Opportunities Number
Project Number
Cognitive decline begins in early stages of Parkinson’s disease (PD) and progresses to dementia in 75% of
people with PD after ten years.
TitleNew Methodologies for Connectomics
Investigator
Xiaotang Lu
Institute
harvard university
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT ABSTRACT
The nervous systems of animals are comprised of neurons connected by a large number of synapses.
The resulting neural networks underlie animal behavior and contribute to the storage of learned
information in many species.
TitleOptical voltage imaging analysis of the cellular and network mechanisms of deep brain stimulation
Investigator
Xue Han
Institute
boston university (charles river campus)
Fiscal Year
Funding Opportunities Number
Project Number
Optical voltage imaging analysis of the cellular and network mechanisms of deep brain stimulation Deep brain stimulation (DBS) directly stimulates brain tissue via implanted electrodes.
TitlePinpointing the Cerebellum's Contribution to Social Reward Processing
Investigator
Haroon Skander Popal
Institute
temple univ of the commonwealth
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT SUMMARY
The cerebellum has long been thought to solely process motor information. Yet, there is a growing literature
that points to a role of the cerebellum in processes across multiple domains.
TitleRole of Endocannabinoid System in Seizure Sensitivity in Eclampsia
Investigator
Maria Jones-Muhammad
Institute
university of mississippi med ctr
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary
Preeclampsia, a hypertensive disorder of pregnancy, can advance to eclampsia, when the mother
displays novel seizures. The mechanisms that cause some preeclampsia patients to advance to
eclampsia are unknown.
TitleRole of neuronal ensembles in cortical plasticity during learning and development
Investigator
Alejandro Akrouh
Institute
columbia univ new york morningside
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary/Abstract
The brain undergoes extensive synaptic plasticity and circuit refinement during development. Similar
changes recur throughout life during learning in a more narrowly constrained manner.
TitleSecondary analysis of resting state MEG data using the Human Neocortical Neurosolver software tool for cellular and circuit-level interpretation
Investigator
Stephanie Ruggiano Jones
Institute
brown university
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary
The neuroscience community is experiencing a revolution in its ability to share and analyze vast amounts of
human brain imaging data, with support from the BRAIN Initiative and other substantial data-sharing efforts.
TitleSpinal Cord Stimulation to Improve Motor Function in People with Post-Stroke Hemiplegia
Investigator
Marco Capogrosso, Douglas J Weber
Institute
university of pittsburgh at pittsburgh
Fiscal Year
Funding Opportunities Number
Project Number
SUMMARY
Motivation: In the US, almost 800’000 people have a stroke every year.
TitleStatistical machine learning tools for understanding neural ensemble representations and dynamics
Investigator
Uri Tzvi Eden, Loren M Frank, Alan David Kaplan
Institute
university of california, san francisco
Fiscal Year
Funding Opportunities Number
Project Number
The brain is a massively interconnected network of specialized circuits.
TitleThe Disadvantage Exposome as a Driver of Alzheimer’s Disease Pathology
Investigator
Margo Heston
Institute
university of wisconsin-madison
Fiscal Year
Funding Opportunities Number
Project Number
1 PROJECT SUMMARY
2 Alzheimer's disease (AD) is the most common form of dementia worldwide, incurring a projected healthcare
3 burden of $1 trillion in the United States alone by 2060.
TitleThe Neural Code and Dynamics of the Reading Network
Investigator
Nitin Tandon
Institute
university of texas hlth sci ctr houston
Fiscal Year
Funding Opportunities Number
Project Number
Reading involves complex transformations of word forms, with visual input mapped to lexical, semantic and
phonological systems in less than a second.
TitleUltra-fast cerebral blood flow imaging for quantifying brain dynamics
Investigator
Jia Guo
Institute
university of california riverside
Fiscal Year
Funding Opportunities Number
Project Number
Abstract/Project Summary
Blood oxygenation level dependent (BOLD) fMRI is widely used in neuroscience studies.
TitleUnderstanding how cortex supports flexible sensory representations
Investigator
Katherine Charlotte Wood
Institute
university of pennsylvania
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary
Learning is a fundamental function of the brain: sensory representations must be flexible to adjust to changes in
environmental demands and experience, thus allowing us to adapt to the world around us.
TitleVirtual observatory of the cortex: organelles, cells, circuits, and dynamics
Investigator
Forrest Christie Collman, Nuno Macarico Da Costa, R Clay Reid, Hyunjune Sebastian Seung
Institute
allen institute
Fiscal Year
Funding Opportunities Number
Project Number
We propose to create VOrtex, a Virtual Observatory for the Cortex: Spanning the Scales of Organelles, Cells,
Circuits, and Dynamics.
TitleWearable RF-EEG Cap for closed loopTMS/fMRI/EEG Applications
Investigator
Lucia Isabel Navarro De Lara
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary
Functional MRI (fMRI) is the prevailing method for both basic research and clinical functional neuroimaging in
humans.
Title3D Functional Photoacoustic Imaging of Human Brain with a Stretchable Ultrasound Matrix Array
Investigator
Yun Jing
Institute
pennsylvania state university, the
Fiscal Year
Funding Opportunities Number
Project Number
Abstract
Many scientific efforts have been devoted to understanding the brain functions, and the relevance of its dynamics
during development, aging, and in diseased conditions. Alterations of the brain functions can result from
multifactorial processes and be reflected by various biomarkers.