This NOFO solicits applications for next generation sensor and bioelectronic device development that will synchronize with brain recordings. The sensor and neural recording data will be used to generate new computational models of behavior in human and animal models. There has been a lack of quantitative approaches and models to understand the complexity of human and animal behavior in naturalistic settings. This NOFO focuses on the development of next generation sensors to acquire data and synchronize it with simultaneous brain recordings to build computational models.
Notices of Funding Opportunities
National Institutes of Health (NIH) BRAIN Initiative notices of funding opportunities (NOFOs), requests for applications (RFAs), program announcements (PAs), and other NIH Guide announcements are listed below. Search this page to find all notices of special interest (NOSI). Search the Closed Opportunities page to find expired opportunities.
Learn more about NIH’s grant mechanisms.
Learn about the Plan for Enhancing Diverse Perspectives (PEDP), a required component in most BRAIN applications.
Learn about the NIH Data Management and Sharing Policy, which all NIH applications must follow.
To see more NIH-funded awards, please visit NIH Grants and Funding.
For more about NIH BRAIN Initiative research and associated funding opportunities, visit the Research Overview.
Title
Release Date
Expiration Date
Funding Opportunity #
Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
January 01 , 2027
Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)
January 01 , 2027
This announcement supports Specialized Projects to develop current or emerging technologies to generate comprehensive atlases of brain connectivity, with an emphasis on human, non-human primate (NHP), and mouse. Projects validating approaches using other species are also permitted if well justified. Applications may address any aspects of the data collection, analysis, and dissemination pipelines, to enable faster and more cost-effective generation and interpretation of brain-wide wiring diagrams. Projects will offer distinct capabilities and competencies aimed at developing and optimizing current technologies or entirely new and potentially risky approaches. They will be integrated into the BRAIN CONNECTS Network, consisting of other Specialized Projects from this FOA, and Comprehensive Centers from its companion announcements, as a coordinated effort aimed at developing wiring diagrams that can span entire brains across multiple scales.
Notice of Termination of RFA-NS-24-028: BRAIN Initiative Connectivity across Scales Data Coordinating Center (BRAIN CONNECTS DCC) (U24 Clinical Trial Not Allowed)
January 01 , 2027
Expiring this NOFO.
Notice of Change to Institutional Applicant Eligibility for RFA-NS-24-030: NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
January 01 , 2027
Allowing intramural applicants.
OPEN House webinar for RFA-NS-24-030: NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
January 01 , 2027
Graduate students and their mentors are invited to take part in a virtual OPEN House that will provide attendees resources for preparing an application for the NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) (RFA-NS-24-030).
Notice of Change: Cancelation of RFA-NS-23-024 "BRAIN Initiative: Targeted BRAIN Circuits Projects- TargetedBCP (R01 Clinical Trial Not Allowed)"
January 01 , 2027
Canceling NOFO.
Notice of Change: Cancelation of RFA-NS-22-041 "BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01 Basic Experimental Studies with Humans Required)"
January 01 , 2027
Canceling NOFO.
Notice of Change: Cancelation of RFA-NS-23-025 "BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trials Optional)"
January 01 , 2027
Canceling NOFO.
Notice of Change to receipt date for RFA-NS-23-023: BRAIN Initiative: Targeted BRAIN Circuits Planning Projects TargetedBCPP (R34 Clinical Trials Not Allowed)
January 01 , 2027
Canceling the June 2024 receipt date.
Request for Information (RFI): BRAIN Initiative: Opportunities and Challenges for Coordinated Neural Stimulating and Recording Efforts to Advance Understanding of Human Neuroscience and Behavior
January 01 , 2027
This is a Request for Information (RFI) from the NIH BRAIN Initiative that solicits input about advancing human neuroscience research on brain-behavior relationships through coordinated efforts involving neural stimulation and recording.
This RFI seeks input from scientific research communities, healthcare providers, patient advocacy groups, people with lived experience of brain or behavioral health disorders, educators, and other interested parties. The NIH encourages organizations (e.g., patient advocacy groups, professional organizations) to submit a single response reflective of the views of the organization and membership as a whole.