Notices of Funding Opportunities

National Institutes of Health (NIH) BRAIN Initiative notices of funding opportunities (NOFOs), requests for applications (RFAs), program announcements (PAs), and other NIH Guide announcements are listed below. Search this page to find all notices of special interest (NOSI). Search the Closed Opportunities page to find expired opportunities.  

Learn more about NIH’s grant mechanisms.  

Learn about the Plan for Enhancing Diverse Perspectives (PEDP), a required component in most BRAIN applications.  

Learn about the NIH Data Management and Sharing Policy, which all NIH applications must follow.  

To see more NIH-funded awards, please visit NIH Grants and Funding.

For more about NIH BRAIN Initiative research and associated funding opportunities, visit the Research Overview.

Title
Release Date
Expiration Date
Funding Opportunity #
Notice of Change to Institutional Applicant Eligibility for RFA-NS-24-030: NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
January 01 , 2027
Allowing intramural applicants.
OPEN House webinar for RFA-NS-24-030: NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
January 01 , 2027

Graduate students and their mentors are invited to take part in a virtual OPEN House that will provide attendees resources for preparing an application for the NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) (RFA-NS-24-030).

Notice of Change: Cancelation of RFA-NS-23-024 "BRAIN Initiative: Targeted BRAIN Circuits Projects- TargetedBCP (R01 Clinical Trial Not Allowed)"
January 01 , 2027
Canceling NOFO.
Notice of Change: Cancelation of RFA-NS-22-041 "BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01 Basic Experimental Studies with Humans Required)"
January 01 , 2027
Canceling NOFO.
Notice of Change to receipt date for RFA-NS-23-023: BRAIN Initiative: Targeted BRAIN Circuits Planning Projects TargetedBCPP (R34 Clinical Trials Not Allowed)
January 01 , 2027
Canceling the June 2024 receipt date.
Notice of Change: Cancelation of RFA-NS-23-025 "BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trials Optional)"
January 01 , 2027
Canceling NOFO.
Request for Information (RFI): BRAIN Initiative: Opportunities and Challenges for Coordinated Neural Stimulating and Recording Efforts to Advance Understanding of Human Neuroscience and Behavior
January 01 , 2027
This is a Request for Information (RFI) from the NIH BRAIN Initiative that solicits input about advancing human neuroscience research on brain-behavior relationships through coordinated efforts involving neural stimulation and recording. This RFI seeks input from scientific research communities, healthcare providers, patient advocacy groups, people with lived experience of brain or behavioral health disorders, educators, and other interested parties. The NIH encourages organizations (e.g., patient advocacy groups, professional organizations) to submit a single response reflective of the views of the organization and membership as a whole.
Notice of Change to Award Budget for RFA-NS-24-014 "NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) (R25 Clinical Trial Not Allowed)"
January 01 , 2027
The purpose of this notice is to inform applicants of a clarification to the Award Budget for RFA-NS-24-014 "NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) (R25 Clinical Trial Not Allowed)".
Notice of Change: Extension of RFA-NS-24-028 - BRAIN Initiative Connectivity across Scales Data Coordinating Center (BRAIN CONNECTS DCC) (U24 Clinical Trial Not Allowed)
August 22 , 2024
The purpose of this notice is to extend RFA-NS-24-028BRAIN Initiative Connectivity across Scales Data Coordinating Center (BRAIN CONNECTS DCC) (U24 Clinical Trial Not Allowed) by one additional council round. An additional receipt date, August 21, 2024, has been added and the new expiration date is August 22, 2024.
Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace
April 06 , 2027
This Notice of Special Interest (NOSI) encourages the translation of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative-supported technologies from academic and other non-small business research sectors to the marketplace. Small Business Concerns (SBCs) are encouraged to submit Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grant applications that propose to further develop, optimize, validate and scale such technologies for commercial dissemination. Additionally, SBIR and STTR applications supporting the development and commercialization of novel technologies that fit within the mission of the BRAIN Initiative are encouraged.