Electroencephalography (EEG) measures the brain’s local field potential from the surface of the scalp. This method is useful for studying cognitive processes, neurological states, and medical conditions.
Funded Awards
The National Institutes of Health (NIH) BRAIN Initiative funds a wide-variety of research: toolmakers, trainees, individual labs testing new hypotheses, and large, team-based efforts aiming to catalyze neuroscience inquiry forward. Explore NIH BRAIN Initiative funded awards listed below. Click on the project title to learn more about it within NIH RePORTER.
To see more NIH-funded awards and associated publications, please visit the NIH RePORTER.
Title
Investigator(s)
Institution
Fiscal Year
Funding Opportunity #
Project #
Title
A Dry Electrode for Universal Accessibility to EEG
Investigator
Walid Soussou
Institute
quasar, inc.
Fiscal Year
Funding Opportunities Number
Project Number
Title
A germline- and promoter-independent strategy to gain access to all cell types in the brain
Investigator
Huaiyu Hu, Yingxi Lin, Baisong Lu
Institute
wake forest university health sciences
Fiscal Year
Funding Opportunities Number
Project Number
Project summary The heterogeneity from the vast number of cell types in the brain presents a major challenge in our understanding of how brain works and in our treatment of neurological disorders.
Title
Advancing fMRI Acquisition through Dissemination of EPTI- An Efficient Distortion-Free Multi-Contrast Imaging Technology
Investigator
Fuyixue Wang
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT SUMMARY / ABSTRACT Functional MRI (fMRI) is today the predominant tool for noninvasive imaging of brain function, which has revolutionized our understanding of the human brain.
Title
An optical-genetic toolbox for monitoring and controlling diverse neuromodulatory circuits governing complex behaviors in primates
Investigator
Karl A. Deisseroth, Eyal J Seidemann
Institute
university of texas at austin
Fiscal Year
Funding Opportunities Number
Project Number
ABSTRACT Perceptually guided behavior involves a complex and dynamic interplay between external inputs and internal states that are related, for example, to alertness, motivation, expectations and attention.
Title
Analysis of modulation of the metabotropic glutamate receptor type 5 in a novel heritable model of drug abuse vulnerability
Investigator
Loren D Peeters
Institute
east tennessee state university
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary Schizophrenia is a debilitating mental illness affecting an estimated 1% of the global population.
Title
Beyond dopamine: dual neuromodulator regulation of motor variability and learning
Investigator
Drew Clinton Schreiner
Institute
duke university
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary Learning and performing complex skills such as speech or music requires precise control of motor variability. While elevated motor variability can spur the learning of new behaviors, excessive variability can impair performance of learned skills.
Title
Biophysical Mechanisms of Cortical MicroStimulation
Investigator
Sydney S Cash, Mark Thomas Harnett
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number
Project Number
Direct local electrical stimulation (DLES) is an increasingly important therapeutic tool for treating brain disorders such as Parkinson’s, epilepsy, and OCD.
Title
Boss: A cloud-based data archive for electron microscopy and x-ray microtomography
Investigator
Brock A. Wester
Institute
johns hopkins university
Fiscal Year
Funding Opportunities Number
Project Number
ABSTRACT The generation of scientifically rich, high resolution neuroimaging volumes continues to increase in extent and rate due to the advancement of new Electron Microscopy (EM) and X-ray Microtomography (XRM) imaging sys- tems and data processing methodologies.
Title
Bottom-Up, Top-Down, and Local Interactions in the Generation and Consolidation of Cortical Representations of Sequential Experience
Investigator
Bruce L Mcnaughton
Institute
university of california-irvine
Fiscal Year
Funding Opportunities Number
Project Number
Years of study and theory about the unique role of the hippocampus in storing new memories has led to a general idea that the hippocampus generates a unique output code for every unique experience, that is projected back to the neocortex, where it becomes coupled to attributes of the experience t
Title
BRAIN CONNECTS: A Center for High-throughput Integrative Mouse Connectomics
Investigator
Jeff W Lichtman
Institute
harvard university
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary/Abstract The proposed project will demonstrate the feasibility of generating a complete synapse-level brain map (connectome) by developing a serial-section electron microscopy pipeline that could scale to a whole mouse brain.
Title
BRAIN CONNECTS: Center for a pipeline of high throughput integrated volumetric electron microscopy for whole mouse brain connectomics
Investigator
Forrest Christie Collman, Nuno Macarico Da Costa
Institute
allen institute
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary: Center for whole mouse brain connectomics using high-throughput integrated volumetric electron microscopy (HIVE) Two fundamental components of the structural basis of brain function are cell type composition and the wiring diagram between those cells.
Title
BRAIN CONNECTS: Center for Mesoscale Connectomics
Investigator
Taner Akkin, Damien A Fair, Sarah Rachel Heilbronner, Christophe Lenglet, Kamil Ugurbil, Essa Yacoub, Jan Zimmermann
Institute
university of minnesota
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT SUMMARY To understand complex neural pathways and networks and their remarkable ability to generate human behaviors, it is critical to precisely map brain connectomics in vivo.
Title
BRAIN CONNECTS: Comprehensive regional projection map of marmoset with single axon and cell type resolution
Investigator
Guoping Feng, Partha Pratim Mitra, Xiao Wang
Institute
massachusetts institute of technology
Fiscal Year
Funding Opportunities Number
Project Number
SUMMARY This ambitious proposal will establish an integrated experimental-computational platform to create the first comprehensive brain-wide mesoscale connectivity map in a non-human primate, the common marmoset (Callithrix jacchus),.
Title
BRAIN CONNECTS: Mapping brain-wide connectivity of neuronal types using barcoded connectomics
Investigator
Xiaoyin Chen, Justus M Kebschull, Ian R Wickersham
Institute
allen institute
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary Mapping the brain-wide connections of neurons provides a foundation for understanding the structure and functions of a brain.
Title
BRAIN CONNECTS: Mapping Connectivity of the Human Brainstem in a Nuclear Coordinate System
Investigator
Bruce Fischl, Patrick R Hof, Hui Wang
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary/Abstract (30 lines of text limit) The ~1 billion neurons that form the human brainstem are organized at multiple scales, ranging from their cell type-specific patterns of dendritic arborization, to local circuits embedded within large-scale projection systems spanning the brainste
Title
BRAIN CONNECTS: Multi-beam transmission electron microscopy of iteratively milled semi-thick tissue sections
Investigator
Andreas Schaefer, Adrian Andreas Wanner
Institute
paul scherrer institut psi
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary/Abstract Volume electron microscopy is the only technique to-date that provides both sufficient resolution (100 μm) for the dense reconstruction of neuronal wiring diagrams.
Title
BRAIN CONNECTS: PatchLink, scalable tools for integrating connectomes, projectomes, and transcriptomes
Investigator
Tim M Jarsky, Staci A Sorensen, Uygar Sumbul
Institute
allen institute
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary / Abstract Upcoming brain-wide descriptions of synaptic connectivity are poised to transform our understanding of brain circuitry in the same way single-cell genomics has revolutionized our understanding of cell type diversity.
Title
BRAIN CONNECTS: Rapid and Cost‐effective Connectomics with Intelligent Image Acquisition, Reconstruction, and Querying
Investigator
Jeff W Lichtman, Hanspeter Pfister, Aravinthan D. Samuel, Nir Shavit, Brock A. Wester
Institute
harvard university
Fiscal Year
Funding Opportunities Number
Project Number
SUMMARY High-throughput connectomics is needed to generate the TB-, PB- and EB-scale wiring diagrams of mammalian brains, but is limited to the few research institutes (e.g., Janelia, Allen, Max Planck) with sufficient infrastructure.
Title
BRAIN CONNECTS: Synaptic resolution whole-brain circuit mapping of molecularly defined cell types using a barcoded rabies virus
Investigator
Andreas Tolias, Anthony M Zador
Institute
baylor college of medicine
Fiscal Year
Funding Opportunities Number
Project Number
ABSTRACT Single-cell transcriptomics has revolutionized our understanding of neuronal diversity and enabled high-throughput characterization of molecular cell types across brain areas and species.
Title
BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)
Investigator
Suzanne N Haber, Elizabeth M. C. Hillman, Anastasia Yendiki
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number
Project Number
Project summary: This project will develop and validate a comprehensive toolset of novel technologies for imaging axonal projections across scales, and will deploy this toolset to map a complex system of cortico- subcortical projections in the macaque and human brain.