DESCRIPTION (provided by applicant): Behaviors are sequences of actions that are executed in the proper order and correct setting to achieve a goal.
Funded Awards
The National Institutes of Health (NIH) BRAIN Initiative funds a wide-variety of research: toolmakers, trainees, individual labs testing new hypotheses, and large, team-based efforts aiming to catalyze neuroscience inquiry forward. Explore NIH BRAIN Initiative funded awards listed below. Click on the project title to learn more about it within NIH RePORTER.
To see more NIH-funded awards and associated publications, please visit the NIH RePORTER.
Title
Investigator(s)
Institution
Fiscal Year
Funding Opportunity #
Project #
Title
Lagging or Leading? Linking Substantia Nigra Activity to Spontaneous Motor Sequences
Investigator
Ryan Prescott Adams, Sandeep R Datta, Bernardo L Sabatini
Institute
harvard medical school
Fiscal Year
Funding Opportunities Number
Project Number
Title
MULTISCALE ANALYSIS OF SENSORY-MOTOR CORTICAL GATING IN BEHAVING MICE
Investigator
Dieter Jaeger, Garrett B. Stanley
Institute
emory university
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): To address the core question underlying the Obama Brain Initiative to better understand the function of complex brain circuits, we propose a multi-scale recording and data analysis project to study the dynamical interactions between sensory cortex, motor cor
Title
Multiscale Imaging of Spontaneous Activity in Cortex: Mechanisms, Development and Function
Investigator
R Todd Constable, Michael C. Crair
Institute
yale university
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): The purpose of this RFA is to promote the integration of experimental, analytic and theoretical capabilities for the examination of neural circuits and systems.
Title
Network basis of action selection
Investigator
Anatol Kreitzer, Takaki Komiyama, Byungkook Lim
Institute
j. david gladstone institutes
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): The anatomical substrates and cellular mechanisms underlying reward-dependent learning have been studied for decades, but the specific circuit and network interactions between the cortex, striatum, and midbrain that mediate action selection have not been sys
Title
Neural ensembles underlying natural tracking behavior
Investigator
Ila R. Fiete, Alexander C Huk, Nicholas J Priebe
Institute
university of texas at austin
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): The system that controls smooth pursuit eye movements is one of the most accessible, promising systems for understanding how neural circuits transform sensory inputs into actions.
Title
Behavioral readout of spatiotemporal codes dissected by holographic optogenetics
Investigator
Dmitry Rinberg, Shy Shoham
Institute
new york university school of medicine
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): Two of the most fundamental questions of sensory neuroscience are: 1) how is stimulus information represented by the activity of neurons at different levels of information processing?
Title
Cortical circuits and information flow during memory-guided perceptual decisions
Investigator
Mriganka Sur
Institute
massachusetts institute of technology
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): Perceptual decision-making involves multiple cognitive components and diverse brain regions.
Title
Crowd coding in the brain:3D imaging and control of collective neuronal dynamics
Investigator
Patrick O Kanold, Wolfgang Losert, Dietmar Plenz
Institute
univ of maryland, college park
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): The cortex is a laminated structure that is thought to underlie sequential information processing.
Title
Integrative Functional Mapping of Sensory-Motor Pathways
Investigator
Michael H Dickinson, Philip J Holmes, Richard S Mann, Rachel Wilson
Institute
california institute of technology
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): The goal of the project team is to develop a robust, multi-lab research framework, enabled by large scale imaging, which will lead to principled integrative models of ethologically-relevant behaviors that incorporate a detailed knowledge of individual cell c
Title
Mechanisms of neural circuit dynamics in working memory
Investigator
William Bialek, Carlos D Brody, Hyunjune Sebastian Seung, David W Tank, Samuel Sheng-Hung Wang, Ilana Witten
Institute
princeton university
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): Working memory, the ability to temporarily hold multiple pieces of information for mental manipulation, is central to virtually all cognitive abiliies.
Title
Neural circuits in zebrafish: form, function and plasticity
Investigator
Constance L Cepko, Florian Engert, Jeff W Lichtman, Haim Sompolinsky
Institute
harvard university
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): We propose to combine whole brain 2-photon imaging of neural activity in behaving larval zebrafish with detailed anatomical and connectivity information extracted from the same animals.
Title
Revealing the connectivity and functionality of brain stem circuits
Investigator
Darwin K Berg, Martin Deschenes, Yoav Shai Freund, Martyn D Goulding, David Kleinfeld, Per M Knutsen
Institute
university of california, san diego
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): Neuronal circuits in the brainstem control life-sustaining functions, in addition to driving and gating active sensation through taste, smell, and touch.
Title
The role of patterned activity in neuronal codes for behavior
Investigator
John H.r. Maunsell
Institute
university of chicago
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): A key aspect of brain function is how the activity of neuronal populations encodes information that is used to guide behavior.
Title
Towards a Complete Description of the Circuitry Underlying Memory replay.
Investigator
Ivan Soltesz
Institute
university of california-irvine
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): The function of a brain region is an emergent property of many cell types.
Title
Vertically integrated approach to visual neuroscience: microcircuits to behavior
Investigator
Thomas Euler, Andrew D Huberman, Markus Meister, Hyunjune Sebastian Seung, Rachel O Wong
Institute
princeton university
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): Visual neuroscience is finally beginning to achieve a "vertically integrated" understanding of the retina, bridging all levels from molecules to microcircuits to behavior.