Funded Awards

The National Institutes of Health (NIH) BRAIN Initiative funds a wide-variety of research: toolmakers, trainees, individual labs testing new hypotheses, and large, team-based efforts aiming to catalyze neuroscience inquiry forward. Explore NIH BRAIN Initiative funded awards listed below. Click on the project title to learn more about it within NIH RePORTER.

To see more NIH-funded awards and associated publications, please visit the NIH RePORTER

Title
Investigator(s)
Institution
Fiscal Year
Funding Opportunity #
Title Basic neural processing mechanisms of live human face viewing
Investigator
Megan Kelley
Institute
yale university
Fiscal Year
Funding Opportunities Number
Project Summary Significance. The human brain has a dedicated neural system for processing other humans. However relatively little is known about the basic mechanisms of this processing.
Title BCI-DEF: Brain Computer Interfaces and Disability: Developing an Inclusive Ethical Framework
Investigator
Karen G Hirsch, Holly K Tabor
Institute
stanford university
Fiscal Year
Funding Opportunities Number
Project Summary/Abstract The objective of “Brain Computer Interfaces and Disability: Developing an Inclusive Ethical Framework (BCI- DEF)” is to use structured vignettes, video-supported interviews, and a deliberative democracy approach to assess and analyze diverse, critical stakeholder perspective
Title Bidirectional circuits of locus ceruleus and motor cortex neurons
Investigator
Gordon M Shepherd
Institute
northwestern university at chicago
Fiscal Year
Funding Opportunities Number
Project Summary Primary motor cortex (M1) and the locus ceruleus (LC) both contribute in essential ways to the generation of purposive movements – with M1 and its pyramidal tract (PT) neurons involved in action planning and execution, the and LC and its noradrenergic axonal projections involved in a
Title BRAIN Initiative: Hierarchical Event Descriptors (HED): a system to characterize events in neurobehavioral data
Investigator
Scott Makeig, Kay A Robbins, Arnaud Delorme
Institute
university of california, san diego
Fiscal Year
Funding Opportunities Number
This two-year project will advance, integrate, document, and promote the use of the Hierarchical Event Descriptor (HED) system to describe events in human neuroimaging and behavioral data from research experiments and other sources in sufficient detail to support comparative analysis of human brain
Title BRAIN Integrated Resource for Human Anatomy and Intracranial Neurophysiology
Investigator
Dominique Duncan, Nader Pouratian
Institute
ut southwestern medical center
Fiscal Year
Funding Opportunities Number
PROJECT SUMMARY/ABSTRACT Intracranial recordings in patients undergoing neurosurgical interventions provide a unique opportunity to directly access, study, and learn about both normal human brain function and neuropsychiatric disease.
Title CAJAL: A computational framework for the combined morphometric, transcriptomic, and physiological analysis of cells
Investigator
Pablo Gonzalez Camara
Institute
university of pennsylvania
Fiscal Year
Funding Opportunities Number
ABSTRACT Morphology is an essential phenotype in the characterization of cells and their states. It reflects the progression of functional cellular processes, such as morphogenesis, migration, or dendrite arborization, and can be indicative of disease.
Title Caring for BRAIN pioneers: Understanding and enhancing family and researcher support in neural device trials
Investigator
Sara Goering, Eran Klein
Institute
university of washington
Fiscal Year
Funding Opportunities Number
Project abstract BRAIN pioneers are people who take on significant risk as participants in first-in-human or early neurotechnology studies for the sake of helping to further science.
Title Circuit dynamics of structuring episodic memories in humans
Investigator
Jie Zheng
Institute
boston children's hospital
Fiscal Year
Funding Opportunities Number
Project summary Our lives unfold over time, weaving rich, dynamic, and multisensory information into a continuous experience. However, we remember this as a series of discrete events. For example, the memory of a two-hour movie consists of a few memorable moments tied to the main story.
Title Circuits for spontaneous behavior and phototaxis in a simple model chordate
Investigator
William Smith
Institute
university of california santa barbara
Fiscal Year
Funding Opportunities Number
This proposal will investigate neural circuits driving negative phototaxis in an emerging model for neural circuit analysis: larvae of the primitive chordate Ciona. Ciona larvae have a number of features that make them ideally suited for this project.
Title Computational dynamics in neural populations of freely foraging vs. restrained monkeys
Investigator
Dora Angelaki
Institute
new york university
Fiscal Year
Funding Opportunities Number
Summary This proposal will investigate the neural dynamics underlying three-dimensional foraging behavior, with three overarching goals. The first is to evaluate the neural computations of foraging in dynamic environments in naturalistic settings.
Title Computational foundations of active visual sensing
Investigator
Mackenzie Weygandt Mathis, Cristopher M Niell, Zachary Samuel Pitkow, Andreas Tolias
Institute
baylor college of medicine
Fiscal Year
Funding Opportunities Number
Abstract Vision is an active process: we move our head and eyes to explore the sensory world.
Title Computational Tools for assessing mechanisms and functional relevance of divisive normalization
Investigator
Ruben Coen-Cagli
Institute
albert einstein college of medicine
Fiscal Year
Funding Opportunities Number
Project Summary Divisive normalization (DN) is a well-established theory of how interactions between neurons in a circuit modulate the activity of individual neurons.
Title Cortical circuits for the integration of parallel short-latency auditory pathways
Investigator
Hiroyuki Kato, Paul B Manis
Institute
univ of north carolina chapel hill
Fiscal Year
Funding Opportunities Number
PROJECT SUMMARY How our brain achieves coherent perception by integrating information from parallel sensory pathways distributed across space and time remains a central question in neuroscience.
Title CRCNS: Circuit mechanisms of priors and learning during decision making
Investigator
Guangyu Yang
Institute
massachusetts institute of technology
Fiscal Year
Funding Opportunities Number

When learning a new task, both rats and humans exhibit suboptimal behaviors plagued with superstitious ticks and idiosyncratic biases.

Title CRCNS: Deconstructing dynamics of motor cortex in freely moving behavior
Investigator
Paul Nuyujukian
Institute
stanford university
Fiscal Year
Funding Opportunities Number

What operations are performed by the mammalian central nervous systems to coordinate and conduct voluntary movement? Motor systems neuroscience seeks to understand these neural mechanisms.

Title CRCNS: Dynamics of thalamocortical networks during sensory discrimination
Investigator
Mark Allan Reimers
Institute
michigan state university
Fiscal Year
Funding Opportunities Number
Title CRCNS: Evidence-based modeling of neuromodulatory action on network properties
Investigator
Yangyang Wang
Institute
university of iowa
Fiscal Year
Funding Opportunities Number
Title CRCNS: Heterogeneous effects of cognition on perception: unique leverage on circuit mechanisms
Investigator
Marlene Rochelle Cohen, Brent D. Doiron
Institute
university of chicago
Fiscal Year
Funding Opportunities Number
Title CRCNS: Multifocal causal mapping of brain networks supporting human cognition
Investigator
Aapo Nummenmaa
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number

Neuroimaging methods such as functional MRI and magneto- / electroencephalography (MEG/EEG) cannot directly reveal causal relationships between regional brain activity and behavior.

Title CRCNS: Neural Representations of Time Across Scales in Natural and Artificial Networks
Investigator
Marc W Howard
Institute
boston university (charles river campus)
Fiscal Year
Funding Opportunities Number
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