Funded Awards

PROJECT SUMMARY Non-invasive imaging of human brain function plays an important role in advancing neuroscience research and understanding neurological diseases. This need has been met primarily by functional magnetic resonance imaging (fMRI).

PROJECT SUMMARY/ABSTRACT Does the way we hear sounds change when we become parents?

PROJECT SUMMARY Attention is comprised of several component processes, including sustained attention, selective attention, and attentional flexibility.

Summary Functional Magnetic Resonance Imaging data has been a mainstay of neuroscience research for more than two decades, as it allows rapid, continuous, noninvasive monitoring of neuronal function.

ABSTRACT Reproducible findings are essential to scientific advancement. Unfortunately, when fields lack consensus standards for methods, or their implementations, reproducibility tends to be more of an ideal than a reality.

PROJECT SUMMARY Single-cell technologies have revolutionized the characterization of mammalian brains allowing unbiased census of cell types and their transcriptomic and epigenomics signatures.

PROJECT SUMMARY Neurons in the visual cortex form an intricate connectivity structure and topographic arrangement. The structural and morphological organization of the neurons is known to constrain its functional properties.

Project Summary Primate species frequently use social information to inform their decisions, for instance, to help make inferences about potential threats or rewards in the environment.

Understanding the brain is a profound and fascinating challenge, captivating the scientific community and the public alike. The lack of effective treatment for most brain disorders makes training the next generation of neuroscientists, engineers and physicians a key concern.

Project Summary/Abstract Circuits in the brain control motor output to generate the precise behaviors required for survival. Dysfunction of these circuits results in devastating movement disorders such as Parkinson’s disease and amyotrophic lateral sclerosis.

Project Summary A key goal in neuroscience is determining how microcircuit structure predicts circuit function. An intriguing idea, supported by some theoretical models, is that variation in microcircuit composition supports functional specialization.

PROJECT SUMMARY Charcot-Marie-Tooth (CMT) disease is a genetically and clinically heterogeneous group of inherited peripheral neuropathies that is characterized by damage to long motor and sensory axons.

ABSTRACT Substance use disorder is a chronic relapsing disease that is characterized by repeated drug use despite negative consequences.

Project Summary The ability to remember information, whether after short or long delays, is a fundamental human ability.

Project Summary Understanding cell-type-specific gene functions, expression dynamics, and regulatory mechanisms in complex brains is still challenging.

Project Summary Cortical interneurons (cINs) are inhibitory cells that are born in surplus far from the cortex. During prenatal timepoints, cIN precursors migrate into the mouse visual cortex (V1) where only a fraction are selected to survive.

PROJECT SUMMARY/ABSTRACT Many animals rely on spatial cognition for daily survival in order to recognize familiar places and process movements through or between locations. A variety of space-encoding cells in the hippocampus are important for spatial behaviors in mammals.

This project aims to develop the 2P-ActivityScope™, a revolutionary new microscope based on a technological breakthrough called second-generation Scanned Line Angular Projection (SLAP2) two photon laser scanning microscopy that was recently developed by Dr.

PROJECT SUMMARY/ABSTRACT Miniaturized silicon neurochemical probe to monitor brain chemistry.

The cerebellum has been overlooked for its potential for neuromodulation for decades.