The six layers of cortex form distinct computational units that together govern the information flow and
processing required for complex behavior. Hence, unravelling the brain's computational strategies requires
understanding the layer-specific organization of the neocortex.
Funded Awards
The National Institutes of Health (NIH) BRAIN Initiative funds a wide-variety of research: toolmakers, trainees, individual labs testing new hypotheses, and large, team-based efforts aiming to catalyze neuroscience inquiry forward. Explore NIH BRAIN Initiative funded awards listed below. Click on the project title to learn more about it within NIH RePORTER.
To see more NIH-funded awards and associated publications, please visit the NIH RePORTER.
Title
Investigator(s)
Institution
Fiscal Year
Funding Opportunity #
Project #
TitleThe Neuronal Underpinnings of Non-invasive Laminar fMRI
Investigator
Orrin Devinsky, Essa Yacoub
Institute
university of minnesota
Fiscal Year
Funding Opportunities Number
Project Number
TitleMechanism and dosimetry exploration in transcranial electrical stimulation using magnetic resonance current mapping methods.
Investigator
Rosalind J Sadleir
Institute
arizona state university-tempe campus
Fiscal Year
Funding Opportunities Number
Project Number
Project Abstract
Transcranial electrical stimulation (tES) methods, principally transcranial direct current simulation
(tDCS) and transcranial alternating current stimulation (tACS) are neuromodulation techniques that
have been the subject of great recent interest.
TitleA unified cognitive network model of language
Investigator
Nathan E Crone, Nitin Tandon
Institute
university of texas hlth sci ctr houston
Fiscal Year
Funding Opportunities Number
Project Number
Most current approaches to understanding the neural basis of cognitive processes are severely limited in
two respects. First, most commonly used methods do not have the temporal (e.g., fMRI) or spatial (e.g.,
MEG/ EEG) resolution to capture the relevant dynamics.
TitleEFFECTIVE CONNECTIVITY IN BRAIN NETWORKS: Discovering Latent Structure, Network Complexity and Recurrence.
Investigator
Stephen José Hanson
Institute
rutgers the state univ of nj newark
Fiscal Year
Funding Opportunities Number
Project Number
Principal investigator/Program Director (Last, first, middle): Hanson, Stephen, José RFA-EB-15-006
Project Summary/Abstract
Since the earliest days of neuroscience research, core methods have focused on matching specific functions
to local brain structure and neural activity.
TitleFunctional Architecture of Speech Motor Cortex
Investigator
Edward Chang
Institute
university of california, san francisco
Fiscal Year
Funding Opportunities Number
Project Number
PROJECT SUMMARY
Speaking is one of the most complex actions that we perform, yet nearly all of us learn do it effortlessly.
TitleGraph theoretical analysis of the effect of brain tumors on functional MRI networks
Investigator
Andrei I Holodny, Hernan Makse
Institute
city college of new york
Fiscal Year
Funding Opportunities Number
Project Number
Project Summary/Abstract:
The broad, long-term objective of this grant is to advance a graph theoretical framework to identify core-nodes
in a Brain Network of Networks to develop a software tool that will allow end-users from the broad
neuroscience community to identify and analyze the most influen
TitleImaging the Neural Effects of Transcranial Direct Current Stimulation
Investigator
Gottfried Schlaug
Institute
beth israel deaconess medical center
Fiscal Year
Funding Opportunities Number
Project Number
Research investigating the use of noninvasive electrical stimulation (e.g., transcranial direct current
stimulation (tDCS)), for neurologic and psychiatric disorders has provided compelling evidence that such
stimulation can modulate behavior and cognition, and even facilitate recovery of function a
TitleSubthalamic and corticosubthalamic coding of speech production
Investigator
Robert Mark Richardson
Institute
university of pittsburgh at pittsburgh
Fiscal Year
Funding Opportunities Number
Project Number
Speech production and control is disrupted in a number of neurological diseases that involve the basal ganglia.
Notably, hypophonia and hypokinetic dysarthria (characterized by decreased motor gain) are prevalent in
patients with Parkinson's disease (PD).
TitleUnderstanding the Neural Basis of Volitional State through Continuous Recordings in Humans
Investigator
Sydney S Cash
Institute
massachusetts general hospital
Fiscal Year
Funding Opportunities Number
Project Number
ABSTRACT
In the course of a day we naturally make multiple shifts in our overall cognitive state and in our aims and
intents. We go from sleep to awake, from internal dialogue to external communication, from relative immobility
to planned complex movements.
TitleThree Dimensional Holography for Parallel Multi-target Optogenetic Circuit Manipulation
Investigator
Valentina Emiliani, Serge Picaud
Institute
pierre and marie curie university
Fiscal Year
Funding Opportunities Number
Project Number
DESCRIPTION (provided by applicant): Understanding communication between neurons, who is talking to whom, and what language they are speaking, is essential for discovering how brain circuits underlie brain function and dysfunction.