Notices of Funding Opportunities

National Institutes of Health (NIH) BRAIN Initiative notices of funding opportunities (NOFOs), requests for applications (RFAs), program announcements (PAs), and other NIH Guide announcements are listed below. Search this page to find all notices of special interest (NOSI). Search the Closed Opportunities page to find expired opportunities.  

Learn more about NIH’s grant mechanisms.  

Learn about the Plan for Enhancing Diverse Perspectives (PEDP), a required component in most BRAIN applications.  

Learn about the NIH Data Management and Sharing Policy, which all NIH applications must follow.  

To see more NIH-funded awards, please visit NIH Grants and Funding.

For more about NIH BRAIN Initiative research and associated funding opportunities, visit the Research Overview.

Title
Release Date
Expiration Date
Funding Opportunity #
Notice of Change to Funds Available and Anticipated Number of Awards for RFA-MH-21-140, "BRAIN Initiative Cell Census Network (BICCN) Scalable Technologies and Tools for Brain Cell Census (R01 Clinical Trial Not Allowed)"
January 01 , 2027
This notice increases the Funds Available and Anticipated Number of Awards for RFA-MH-21-140.
Notice of Temporary Extension of Eligibility for the BRAIN Initiative Diversity K99/R00 Career Transition Award During the COVID-19 Pandemic
January 01 , 2027
The purpose of this Notice is to inform the extramural community that as a result of disruptions caused by the COVID-19 pandemic, the BRAIN Initiative will be providing up to a two-receipt cycle extension (roughly eight additional months) of eligibility for prospective applicants meeting the requirements for submission of an application to the BRAIN Initiative Advanced Postdoctoral Career Transition Award to Promote Diversity (K99/R00) through the February/March 2021 due dates.
Notice of Change to Key Dates for RFA-NS-19-002 "BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Required)
January 01 , 2027
The purpose of this notice is to inform interested applicants of a change to the Key Dates and the specific research requirements for RFA-NS-19-002 "BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Required)". The dates have been modified to add a new application due date of October 29, 2021. See changes below inbold italics.
Notice of Change to Key Dates for RFA-NS-19-001 "BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01 Clinical Trial Required)"
January 01 , 2027
The purpose of this notice is to inform interested applicants of a change to the Key Dates and the specific research requirements for RFA-NS-19-001 "BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01 Clinical Trial Required)". The dates have been modified to add a new application due date of October 29, 2021. See changes below inbold italics.
Notice of Change to Key Dates for RFA-NS-19-003 "BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Not Allowed)
January 01 , 2027
The purpose of this notice is to inform interested applicants of a change to the Key Dates and the specific research requirements for RFA-NS-19-003 "BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Not Allowed)". The dates have been modified to add a new application due date of October 29, 2021. See changes below inbold italics.
Notice of Change to Key Dates for RFA-NS-18-019 "BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)"
January 01 , 2027
The purpose of this notice is to inform applicants of a change to the Key Dates for RFA-NS-18-019 "BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)". This Funding Opportunity Announcement has been extended by one council round. The dates have been modified to add a New Application Due Date of May 4, 2021.
Notice of Change to Key Dates for RFA-NS-18-020 "BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)"
January 01 , 2027
The purpose of this notice is to inform applicants of a change to the Key Dates for RFA-NS-18-020 "BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)". This Funding Opportunity Announcement has been extended by one council round. The dates have been modified to add a New Application Due Date of May 4, 2021.
Notice to Extend RFA-MH-19-135 - BRAIN Initiative: Development of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in Human and Non-Human Primate Brain (UG3/UH3 Clinical Trial Optional)
January 01 , 2027
The purpose of this Notice is to extend RFA-MH-19-135, BRAIN Initiative: Development of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in Human and Non-Human Primate Brain (UG3/UH3 Clinical Trial Optional)
Notice to Extend RFA-MH-20-135 BRAIN Initiative: Tools to Facilitate High-Throughput Microconnectivity Analysis (R01 Clinical Trial Not Allowed)
January 01 , 2027
The purpose of this Notice is to extend RFA-MH-20-135, BRAIN Initiative: Tools to Facilitate High-Throughput Microconnectivity Analysis (R01 Clinical Trial Not Allowed)
Notice of Change to Key Dates for RFA-NS-18-022 "BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)"
January 01 , 2027
The purpose of this notice is to inform applicants of a change to the Key Dates for RFA-NS-18-022 "BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44 Clinical Trial Required)". This Funding Opportunity Announcement has been extended by one council round. The dates have been modified to add a New Application Due Date of February 22, 2021.
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